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What is Erectile Dysfunction or ED?

What is Erectile Dysfunction or ED?

Erectile Dysfunction or Impotence is condition in which there is inability to keep erection during sexual intercourse. Impotence is broad term which include lack of sexual desire and orgasm.

Causes of erectile dysfunctions are damage to arteries, nerves or smooth muscles of penis. Between 35 and 50 percent of men with diabetes, experience erectile dysfunction.

Patient safety is our number one priority and we assured result.

What causes ED?

Erection causes by hemodynamic combine effect of Corpora cavernosa and the corpus spongiosum. This tissue consist of fibrous tissue, nerves, smooth muscles which increase blood supply.

Lack of blood supply or disturbances in it causes erectile dysfunction.

Vascular insufficiency is the main pathology behind erectile dysfunction.

Currently vasodilators like Viagra and Cialis used to treat erectile dysfunction. These medicines have temporary effect .there are serious side effects like heart attack, Stroke or even death occurred due to this.

Therefore treatments like Platelet-Rich Plasma (PRP) Procedures that address tissue defects and/or vascular disease aspects of erectile dysfunction may provide a longer term therapy or even provide a permanent effect in comparison to other treatments.

ED is frequently related to Diabetes?

Erectile dysfunction is one of complication of long standing Diabetes. Diabetes damage blood vessels and nerves of penile region. ED in diabetes strongly correlates with the level of glucose control, duration of disease and diabetic complications.

Some other causes of ED

Some of the causes other than diabetes are:

Metabolic syndrome (a condition involving increased blood pressure, high insulin levels, body fat around the waist and high cholesterol

Obesity, chronic inflammation,

Low testosterone levels

Tobacco; Alcoholism and other drug abuse

Heart disease, High blood pressure, neurological disease

Peyronie’s disease (development of scar tissue)

Parkinson’s disease, Multiple sclerosis disease

Surgeries or injuries that affect the pelvic area or spinal cord

Medications such as antidepressants, antihistamines and medications to treat high blood pressure, pain or prostate cancer.

Emotional or psychological causes including Depression, Stress, anxiety or other mental health conditions

How is Erectile Dysfunction diagnosed?

It was diagnosed on the basis of complete blood investigations, Doppler study and clinical examinations.

Some of the tests that we may do to diagnose the underlying cause of you ED include:

Complete blood Count

Liver function Test/Kidney function test.

Tests to diagnose any underlying vascular disease.

Urine test.

Hormonal study

Ultrasound to check blood flow to your penis. It involves using a wand-like device (transducer) held over the blood vessels that supply the penis.

Test for Endothelial Integrity – This test is sometimes done in combination with an Ultrasound to determine if there is an increase in the blood flow in response to the medication.

What are the different approaches for treatment of ED?

Drugs and Medical Treatments for ED –

Pharmacological methods: vasodilators like Viagra or Cialis, Having temporary effect with life threatening complications like heart Attack, Stroke or Death.

Other options include – Injectable medicine like Alprostadil, Caverjet, Edex, Alprostadil penis suppository intraurethral (MUSE) and Testosterone replacement (cream or injectable). Penile pumps or a vacuum constriction device and Penile Implants may be options for some patients.

Several alternative treatments are used to treat ED, but more studies are needed to see if these are really effective and safe. These options include: Acupuncture, Korean red ginseng (Panax ginseng); Yohimbine; Ginkgo, L-arginine and DHEA (dehydroepiandrosterone). These herbs can be risky and can interact with your medications or cause other problems.

Now Regenerative medicine Have complete solution to cure Erectile Dysfunction.

Adult Stem Cell Procedure for ED

Stem cells are basic cells of human body, these cells can be differentiate and convert themselves into any type of body cells e.g. heart cells, brain cells or liver cells.

Sources of stem cells are Bone marrow, Adipose tissue (fat) and peripheral blood.

We using your own body stem cells so there are no chances of transmission of infections neither we

Use any Steroid, medicines or laser to activate stem cells, we don’t culture these stem cells.

We follow strict guidelines of FDA.

Properties of stem cells

· These are basic cells of human body, can be differentiate into any type of cells exist in human body.

· Self-renewal: these cells can be renew themselves indefinitely.

· Differentiation: these cells can be convert themselves into any type of cells under appropriate condition e.g. heart cells, brain cells, kidney cells, cartilage etc.

Adipose (Fat) Derived Stem Cells – ADSC

Fat is rich source of mesenchymal stem cells.

We aspirate fat tissue under local anesthesia by using small syringe, it will take half an hour maximum to complete procedure.

Procedure is completely painless without scar.

Then we centrifuge fat tissue to get stromal vascular fraction and mesenchymal stem cells.

Bone Marrow Stem Cells

Bone marrow contains stem cells; primarily hematopoietic stem cells. Bone marrow is harvested from the hip (iliac crest) using local anesthetic and a specialized needle. It is important to understand that

Bone marrow harvesting is vastly different from bone marrow harvesting for transfusion for cancer therapies. In bone marrow harvesting for transfusion, a hematologist, oncologist, or surgeon removes a very large amount of bone marrow. BMAC requires only a very small amount of bone marrow. Surprisingly, the procedure is not painful, takes under ten minutes, and causes only mild soreness afterward. It has an excellent safety profile.

Platelet-Rich Plasma (PRP)

PRP is an acronym for Platelet Rich Plasma. Plasma is essentially blood without the red blood cells. Platelets are cells found in the blood that are essential for clot formation and wound healing. PRP, the mix of concentrated platelets and serum, contains factors that promote repair of tissues. PRP is injected into the targeted area for repair.

Packed with growth and healing factors, platelets initiate repair and attract the critical assistance of stem cells. PRP therapy’s natural healing process, by providing required growth factors, intensifies the body’s efforts to renew and rejuvenate your aging face. To create PRP therapy, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The concentrated platelet rich plasma (PRP) is then injected into and around the point of injury, jump-starting and significantly strengthening the body’s natural healing signal.

The Procedure:

During Procedure for the treatment of ED, we combine your own adult stem cells from bone marrow and fat with PRP. Stem Cells use your body’s own natural reparative factors to harness the healing resources of the body to repair injured tissues. PRP secrete growth factors and send signals which boost the natural healing process in the body. Stem cells not only secrete growth factors and other intercellular signals to command and coordinate the repair process, they can also replace and regenerate tissues by themselves directly.

After we obtain bone marrow aspirate and blood, these are then spun in special centrifuge at specific G-force. The stem cells and PRP are then separated respectively. Lipoaspirate is decanted and fat stem cells are then taken out and mixed with PRP and BMAC. All this is done in strict sterile environment. For most procedures, we blend PRP, ADSC, and BMAC.

Hormone supplementation

We also use hormone supplementation (only if medically indicated).

Results:

Results are usually visible in 2 to 4 weeks and improve gradually over months with improvement in erection and performance.

Expect minimal swelling, bruising and redness for 12-24 hours after the procedure. There can also be some pinkness or redness of the skin following the therapy.

Treatment results vary and some patients may require PRP booster, however in most patients the results last for several years.

Does it leave scars?

No.

Do I need to be put to asleep?

Now use local anesthesia and sedation if patient is anxious.

Is it safe?

100 % safe.

Is it painful?

Minor pain that is also managed by analgesic medicine and local anesthesia.

How long is the recovery?

You will be able to resume your normal daily life immediately.

Swelling may or may not at local site for next 3-4 days.

How long will the result last?

The results should last for several years. The results are affected by your lifestyle, habits and genetics. Smoking and weight fluctuations diminish the results.

Is Stem Cell Therapy Approved by FDA?

FDA does not regulate medical procedures performed by qualified and licensed doctors. Currently, there are no clear protocols to treat any disease with adult stem cells in the India or U.S. We ONLY use your own adult stem cells (not embryonic stem cells) and we don’t alter, manipulate or store your stem cells and we use your cells during the same procedure – therefore FDA does not object to these procedures.

Does insurance cover these procedures? What is the cost?

These procedures are not covered by health insurance plans.

One of the questions that many people have is “how much does this procedure to treat my ED cost?”

Cost is affordable and minimum as compare to other clinics in the world.

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