Duchene Muscular Dystrophy (DMD):
This is cause because of lack of dystrophin gene function in skeletal muscles.
Dystrophin gene regulate proper functioning of dystrophin protein Which is responsible for muscle functioning, due to lack of Dystrophin gene muscles would be weak & fragile .
Causes: this is genetic disorders & passed from parent to next progeny, mostly affected boys, female could be carrier.
It was found that in female one X gene was normal & second X gene could be carrier.
Sign & symptoms:
It start showing symptoms at early age around 3-4 years onwards. Initially affect proximal upper & lower limbs then distal limbs.
Muscle weakened & flaccid, running, walking wouldn't possible.
Prognosis is very bad, patient could survive up to age of 20.
Mainly respiratory & cardiac muscles affected.
Stem Cell Therapy:
Stemmedica India providing Stem cell & gene therapy for Duchene Muscular Dystrophy., We have been treated more than 2000 muscular dystrophy patients successfully by stem cell therapy in India.